Laura Cervera, PhD student, under the direction of Prof. Valentín Ceña, participated in a session entitled: “Nanotechnology and administration of nanocarrier-based drugs as a possible therapeutic strategy for glioblastoma multiforme: an update”, framed in the “Cycle of Sessions Advances in Clinical Laboratory I (1st edition)”, held in the Aula Magna of the University Hospital of Toledo.
In the session, Laura gave a critical reading of a narrative review of an article that talks about a topic that is directly related to her particular project, framed in the Complementary Plans for Biotechnology applied to health in Castilla-La Mancha.
This review provides an overview of the current panorama of glioblastoma multiforme, putting on the table striking survival figures with the treatment that is available today, as it only reaches a survival rate of 4-7%.
In addition, it delves into the different obstacles that researchers encounter when it comes to treating this disease.
There are two fundamentally:
- The per se resistance of glioblastoma stem cells to treatment.
- The high capacity for self-repair and selective permeability of the blood-brain barrier.
One of the alternatives mentioned in the article referred to by the researcher Laura Cervera is precisely the topic assigned in her project, as well as in the Doctoral Thesis : the possibility of using nanocarriers that allow effective drugs to be carried against glioblastoma, increasing selectivity and reducing pharmacological toxicity.
All this highlights the need for further research into new treatments.
Info: Twitter
